Molecular Mechanisms of Tumor Promoting Breast Fibroblasts.

Rudnick, Jenny.


  • Abstract: Breast cancer is a heterogeneous, multi-factorial disease of aberrant breast development whose etiology relies upon several microenvironmental changes within the tissue. As cancerous cells accumulate within the breast epithelium, fibroblasts within the connective tissue stroma become activated, thereby inducing inflammation, matrix remodeling, and bone marrow derived cell recruitment, wh... read more
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