Neural Correlates of Cognitive Interference in Comorbid Psychiatric Disorders
Jahan, Aava
2019
- The Multi-Source Interference Task (MSIT) is predominantly employed to investigate the mechanisms underlying cognitive interference. This aim of this study was to investigate the neural correlates of cognitive interference in patients with comorbid psychiatric disorders and healthy individuals. We hypothesized that cognitive interference would recruit different brain regions between the two ... read moregroups. We utilized the MSIT (Bush & Shin, 2006) in conjunction with functional magnetic resonance imaging (fMRI). We also performed correlations between fMRI data and self-report scores from the Anxiety Sensitivity Index (ASI), Behavioral Inhibition Subscale (BIS), and Quick Inventory of Depressive Symptomatology (QIDS) (Peterson & Reiss,1987; Peterson & Heilbronner, 1987; Carver & White, 1994; Rush, Trivedi, Ibrahim, Carmody, Arnow, Klein et al. 2003). The dorsal anterior cingulate cortex (dACC), dorsolateral prefrontal cortex (dlPFC), and posterior parietal cortex (PPC) were identified as our a priori regions of interest (ROIs). The groups did not differ on brain activation during MSIT-induced cognitive interference. Furthermore, no significant correlations were observed between neural activation and scores from the ASI, BIS, and QIDS questionnaires. While there were no between group-differences, the within-group activations were different in the patients vs. controls. Hence, we concluded that comorbid psychiatric disorders may share common underlying correlates of cognitive interference.read less
- ID:
- m039kj10n
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- TARC Citation Guide EndNote
