Evaluation of the potential inhibition effect of Paritaprevir on UGT 1A1 enzyme activity using human liver microsomes

Alam, Novera.


  • Abstract: Abstract The treatment landscape of chronic hepatitis C (HCV) has changed substantially over the last decade with the introduction of direct-acting antiviral drugs, creating more options to treat the disease. However, the importance of clinically relevant drug-drug interaction remains a challenge. Paritaprevir has been a successful candidate when used in a multidrug regimen for the treat... read more
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