The role of CRF type-1 receptors in the VTA and DRN in excessive alcohol drinking in rats and mice.

Hwa, Lara.


  • Abstract: The dysregulation of brain stress systems, specifically extrahypothalamic action of corticotropin-releasing factor (CRF) via the type-1 receptor (CRF-R1), is thought to mediate escalated, alcohol drinking. The current study modeled excessive drinking in rodents by offering adult male Long-Evans rats and C57BL/6J mice a choice of 20% ethanol or water for 24 hours intermittently throughout ... read more
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