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Introduction: The phenotypic and functional differences between cells
that initiate human breast tumors (cancer stem cells) and those that comprise the
tumor bulk are difficult to study using only primary tumor tissue. We embarked on
this study hypothesizing that breast cancer cell lines would contain analogous
hierarchical differentiation ... read moreprograms to those found in primary breast
tumors.
Keywords: 5-bromo-2-deoxyuridine, colony-forming unit, dimethyl
sulfoxide, epithelial-specific antigen, 5-fluorouracil, nonobese diabetic,
phosphate-buffered saline, severe combined immunodeficient.
Springer Open.read less
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