The Endogenous Retroviral Transcriptome in Melanoma

Roy, Farrah.


  • Abstract: Human endogenous retroviruses (HERVs) are retroviral sequences passed from parent to offspring in a Mendelian fashion. Due to relatively recent endogenization and correlation to human illness, interest in the HERV-K (HML-2) subclade has increased. Expression of HML-2 - specific transcripts and proteins in melanoma cell lines was first discovered about a decade ago. Since there are at lea... read more
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