Background: Previous research suggests that individuals with posttraumatic stress disorder (PTSD) preferentially attend to trauma-related emotional stimuli and have difficulty completing unrelated concurrent tasks. Compared to trauma-exposed control groups, individuals with PTSD also exhibit lower rostral anterior cingulate cortex (rACC) acti... read morevation during tasks involving interference from trauma-related stimuli. However, it is not clear whether relatively diminished rACC activation in PTSD also occurs during interference tasks involving trauma-unrelated emotional stimuli. The present study employed functional magnetic resonance imaging (fMRI) and an interference task that involves emotional facial expressions and elicits rACC activation in healthy participants.
Offringa, Reid, Kathryn Handwerger Brohawn, Lindsay K. Staples, Stacey J. Dubois, Katherine C. Hughes, Danielle L. Pfaff, Michael B. VanElzakker, F. Caroline Davis, and Lisa M. Shin. "Diminished rostral anterior cingulate cortex activation during trauma-unrelated emotional interference in PTSD." Biology of Mood & Anxiety Disorders 3, no. 1 (12, 2013): 1-6.