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Abstract: C-X3-C motif chemokine receptor 1 (CX3CR1) is a G protein-coupled
chemokine receptor and a key regulator of neuroinflammation and response to injury. This
GPCR is considered a putative therapeutic target in diseases associated with inflammation.
CX3CR1 is thought to modulate inflammation in the central nervous system (CNS) and
cardiovascular system. The endogenous ligand for this rec... read more