A Study of the Membrane Anchored Chemokine CX3CL1 and Its Receptor CX3CR1

Ni, Wendi.


  • Abstract: C-X3-C motif chemokine receptor 1 (CX3CR1) is a G protein-coupled chemokine receptor and a key regulator of neuroinflammation and response to injury. This GPCR is considered a putative therapeutic target in diseases associated with inflammation. CX3CR1 is thought to modulate inflammation in the central nervous system (CNS) and cardiovascular system. The endogenous ligand for this recepto... read more
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