Regulators of Inflammation in Arthritic Disease Pathogenesis.

Nakamura, Daisy.


  • Abstract: Inflammation is a major cause of cartilage destruction and leads to the imbalance of catabolic and anabolic activities in the arthritic joint. Our aim was to investigate both positive and negative regulators of inflammation involved in arthritic joint disease. As a positive regulator, pigment epithelium derived factor (PEDF) has been reported to have both pro- and anti-inflammatory activ... read more
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