Characterization of polymorphic HERV-K (HML-2) endogenous proviruses in human and gorilla genomes.

Freeman, Michael.


  • The HERV-K (HML-2) endogenous retrovirus (ERV) family is the most recently active group of ERVs in humans, being the only group with human-specific insertions. Some of the human-specific HERV-K (HML-2) proviruses have retained one or more viral open reading frames (ORFs) and have remained insertionally polymorphic in the human population, hinting at recent activity in our lineage. Furthermore, ... read more
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