3D Functional Corneal Stromal Tissue Equivalent Based on Corneal Stromal Stem Cells and Multi-Layered Silk Film Architecture.

Ghezzi, Chiara E.

Marelli, Benedetto.

Omenetto, Fiorenzo G.

Funderburgh, James L.

Kaplan, David, 1953-

2017

Description
  • The worldwide need for human cornea equivalents continues to grow. Few clinical options are limited to allogenic and synthetic material replacements. We hypothesized that tissue engineered human cornea systems based on mechanically robust, patterned, porous, thin, optically clear silk protein films, in combination with human corneal stromal stem cells (hCSSCs), would generate 3D functional corneal... read more
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  • Ghezzi CE, Marelli B, Omenetto FG, Funderburgh JL, Kaplan DL (2017) 3D Functional Corneal Stromal Tissue Equivalent Based on Corneal Stromal Stem Cells and Multi-Layered Silk Film Architecture. PLoS ONE 12(1): e0169504. doi:10.1371/journal.pone.0169504.
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