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This project involves the development of conformationally constrained mimetic peptides, informed by the Loop Finder program developed by the Kritzer Lab, to block the interaction between two subunits of a ubiquitin ligase. This protein-protein interaction is involved in regulating progression from G1 to S phase of the cell cycle and is associated with many types of cancer. Submitted in partial ... read morefulfillment of the grant requirement of the Tufts Summer Scholars Program.read less
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