Rational Design of Inhibitors of Protein-Protein Interactions Based on Computational Grafting of Hot Loops on to Stable Scaffolds.

Bird, Michael J.

2016

Description
  • Peptides and small, well-folded proteins are important and useful classes of molecules for drug development. Structured peptides and small protein scaffolds can be used to recapitulate natural 3D binding epitopes in a number of ways, including the application of covalent “staples” and by grafting epitopes onto a suitable scaffold protein. These methods, among others, require a known 3D binding epi... read more
This object is in collection Subject Permanent URL
ID:
jm2150905
To Cite:
DCA Citation Guide    EndNote
Usage:
Detailed Rights