GLAST regulates glutamate dynamics and interneuron maturation in the developing cortex

Shih, Jennifer.


  • Abstract: The astrocytic glutamate transporters GLAST and GLT-1 are highly expressed in the neocortex and are critical for regulation of extracellular glutamate concentrations. Glutamate, in turn, regulates many aspects of postnatal cortical development. However, the relative contributions and functional roles of GLAST and GLT-1 in the developing postnatal cortex are not well understood. The ... read more
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