Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1.

Howell, Gareth R.

Libby, Richard T.

Marchant, Jeffrey K.

Wilson, Lawriston A.

Cosma, Ioan M.

Smith, Richard S.

Anderson, Michael G.

John, Simon WM.

2007

Description
  • Background: The glaucomas are a common but incompletely understood group of diseases. DBA/2J mice develop a pigment liberating iris disease that ultimately causes elevated intraocular pressure (IOP) and glaucoma. We have shown previously that mutations in two genes, Gpnmb and Tyrp1, initiate the iris disease. However, mechanisms involved ... read more
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  • Howell, Gareth, Richard T. Libby, Jeffrey K. Marchant, Lawriston A. Wilson, Ioan M. Cosma, Richard S. Smith, Michael G. Anderson, and Simon WM John. "Absence of glaucoma in DBA/2J mice homozygous for wild-type versions of Gpnmb and Tyrp1." BMC Genetics 8, no. 1 (12, 2007): 1-10.
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hq37w0915
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