Effects of FMRP loss on dendritic and somatic translation in CA1 pyramidal neurons during memory storage

Barakatalroudaini, Yehya.


  • Fragile X Syndrome is a common inherited monogenetic disorder caused by the epigenetic silencing of the Fmr1 gene located on the X chromosome. The disorder causes cognitive deficits, physical malformations, autistic behavior, and audio-sensitive epilepsy. Despite much research on the pathophysiology of Fragile X Syndrome, there is still no cure. Fragile X Mental Retardation Protein (FMRP), ... read more
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