An in vivo metastasis screen of chromatin modifiers reveals a potential role for dopamine in adrenal and brain colonization.

Dake, Benjamin.


  • Abstract: Metastasis is the ultimate and fatal stage of malignant progression responsible for the vast majority of cancer deaths. Experimentally we know that metastasis is a highly inefficient process with adaptation to the secondary site being the rate limiting step. Experimental systems able to recapitulate colonization of multiple organs are lacking. To better understand this process I established ... read more
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