Rare IL-17A+ Lymphocytes in the Pathogenesis of Spondyloarthritis.

Hossain, Imtiyaz N.

2017-05-24

Description
  • Spondyloarthritis is a family of rheumatic diseases characterized by inflammation in the spine, peripheral joints, skin, intestine and other organs. Systemic overexpression of IL-23 via hydrodynamic minicircle injection in adult B10.RIII mice induces a spondyloarthritis-like disease with high expression of IL-17A, a pro-inflammatory cytokine downstream of IL-23. A previous study identified a rare ... read more
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