2-1 Signaling Drives Pathological Synaptogenesis, Cell Death and Epileptogenic Circuit Reorganization in a Model of Insult-Induced Cortical Malformation

Lau, Lauren.

2017

Description
  • Abstract: Developmental cortical malformations (DCM) are a common cause of pharmacoresistent epilepsy. DCMs are a group of diverse disorders, associated with varied seizure phenotypes and co-morbidities, including cognitive impairments and developmental delays. DCMs can result from genetic mutations, as well as pre- and peri-natal insults. Hypoxia, viral infection, and traumatic injury are the... read more
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