Elucidating Marginal Zone B cell Fate Decisions using Genome-wide Chromatin Accessibility Profiling.

Ahmad, Maimuna S.

2017

Description
  • Differential chromatin accessibility profiles were seen in mature and precursor marginal zone B cells in the spleen following a Notch-inhibitor treatment. The inhibitor treatment also appeared to deplete the population of both marginal zone B cell types, indicating a role for Notch-signaling in the survival of these cells. Gene expression analysis is required to further elucidate the significance ... read more
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