Elastogenesis in Adult Cells: The Surprising Relationship to Alzheimer's Disease, and Implications for Tissue Engineering.

Saitow, Cassandra.


  • Abstract: Elastic fibers are critical for mechanical integrity of extensible organs such as lungs, skin, and blood vessels. Elastin expression is limited to early developmental stages, as the protein has an extremely long half-life and can therefore persist for the lifetime of the animal. Thus, complications arise in the event of disease or injury, as mechanically sound elastic fibers are not prod... read more
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