Impaired autophagy in mouse embryonic fibroblasts null for Krüppel-like Factor 4 promotes DNA damage and increases apoptosis upon serum starvation.

Liu, Changchang.

DeRoo, Elise P.

Stecyk, Catherine.

Wolsey, Margaret.

Szuchnicki, Mateusz.

Hagos, Engda G.

2015

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  • Background: Autophagy is a major cellular process by which cytoplasmic components such as damaged organelles and misfolded proteins are recycled. Although low levels of autophagy occur in cells under basal conditions, certain cellular stresses including nutrient depletion, DNA damage, and oxidative stress are known to robustly induce auto... read more
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  • Liu, Changchang, Elise P. DeRoo, Catherine Stecyk, Margaret Wolsey, Mateusz Szuchnicki, and Engda G. Hagos. "Impaired autophagy in mouse embryonic fibroblasts null for Krüppel-like Factor 4 promotes DNA damage and increases apoptosis upon serum starvation." Molecular Cancer 14, no. 1 (12, 2015): 1-13.
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