Crucial Role of the Mammalian Target of Rapamycin (mTOR) in Activation of Human Microglia, Mast Cells and Keratinocytes, Inhibitable by Methoxyluteolin.

Patel, Arti.

2016

Description
  • Abstract: Activation of microglia, the resident immune cells of the brain and increased levels of pro-inflammatory cytokines and chemokines have been reported in patients with Autism Spectrum Disorders (ASD); however the stimulus is unknown. Inflammation of the brain in ASD could result from cross-talk between microglia and mast cells (MC), the unique immune cells responsible for allergic and infl... read more
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