Role of the Srs2 helicase and Ctf18 clamp loader in replication of structure-forming CAG repeats in S. cerevisiae

Nguyen, Jennifer.


  • Abstract: Our genome is riddled with repetitive sequences. While the functions of these repetitive sequences largely remain elusive, expansions of a subset of structure-forming microsatellites have been found to be associated with the onset of several neurodegenerative diseases. These repeat sequences pose a natural threat to the cell during replication and repair, forming barriers that can interf... read more
This object is in collection Corporate name Permanent URL
Component ID:
To Cite:
DCA Citation Guide    EndNote