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This is an undergraduate thesis written in for the Tufts Chemistry Department. All research was conducted at the Amy Yee Lab at the Tufts University Sackler School of Biomedical Sciences. This thesis examines the molecular effects of treating triple negative breast cancer with epigallocatechin 3-gallate (EGCG), a compound isolated from green tea, and decitabine (DAC), a chemotherapeutic DNA demeth... read moreylating agent. Using RNA sequencing, a transcriptomic bioinformatic analysis was employed to examine other pathways impacted by EGCG/DAC treatment.read less
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