Synthetic bioreducible lipid-based nanoparticlesfor miRNA delivery to mesenchymal stem cells to induceneuronal differentiation.

Wang, Ming.

Takeda, Yuji S.

Xu, Qiaobing.

Deng, Pu.


  • MicroRNA (miRNA) functions in tissue regeneration and determines the fate of stem cells. Nanoparticle-based miRNA delivery systems for therapeutic applications have been studied in clinical settings. However, gene delivery to stem cells is still a challenging issue. Lipid-like nanoparticles produced using combinatorial approaches have recently been used for delivery of a variety of biologics. In ... read more
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  • Takeda, Y. S., Wang, M., Deng, P. and Xu, Q. (2016), Synthetic bioreducible lipid-based nanoparticles for miRNA delivery to mesenchymal stem cells to induce neuronal differentiation. Bioengineering & Translational Medicine. doi:10.1002/btm2.10021.
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