High-Throughput Screening of Yeast Display Libraries for the Development of Matrix Metalloproteinase Inhibitors

Ghadban, Christopher.


  • Abstract: Matrix metalloproteinases (MMPs) have long been considered promising therapeutic targets to understand and combat cancer development and progression. Given the similarity of their structures and enzymatic functions, but the considerable variation of their pro-tumorigenic or tumorigenic suppressive effects, small molecules have proven unsuccessful as therapeutics, and more specific ... read more
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