Background: Toll-like receptors (TLRs) are pattern recognition receptors
(PRRs) considered to be the primary sensors of pathogens in innate immunity. Genetic
variants could be associated to differences in breed innate immune response to
pathogens and thus to susceptibility to infections or autoimmune diseases. There is
therefore great int... read moreerest in the characterization of canine TLRs.
Cuscó, Anna, Armand Sánchez, Laura Altet, Lluís Ferrer, and
Olga Francino. "Non-synonymous genetic variation in exonic regions of canine
Toll-like receptors." Canine Genetics and Epidemiology 1, no. 1 (12, 2014):