Probabilistic strain optimization under constraint uncertainty.

Hassoun, Soha.

Yousofshahi, Mona.

Orshansky, Michael.

Lee, Kyongbum.

2013

Description
  • Background: An important step in strain optimization is to identify reactions whose activities should be modified to achieve the desired cellular objective. Preferably, these reactions are identified systematically, as the number of possible combinations of reaction modifications could be very large. Over the last several years, a number of computational methods have been described for identifying... read more
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  • Yousofshahi et al.: Probabilistic strain optimization under constraint uncertainty. BMC Systems Biology 2013 7:29. doi: 10.1186/1752-0509-7-29.
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