Investigating the canonical Wnt signaling pathway in hematopoiesis: revisiting the role of Tcf-1 in early lymphoid development.

Germar, Kristine.

2012

Description
  • Abstract: In hematopoiesis, the transcriptional networks governing lineage choice from pluripotent progenitors to mature lymphoid cells remain poorly understood. Although some key factors associated with the specification and commitment of T cells have been described, the functional hierarchy and the roles of key regulators in orchestrating these developmental programs remain unclear. While a loss... read more
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