Notch signaling in the adult olfactory epithelium: roles in stem cell quiescence, lineage specification, and neuronal maturation

Herrick, Daniel.

2018

Description
  • Abstract: The adult olfactory epithelium (OE) has the remarkable capacity to regenerate fully both neurosensory and non-neuronal cell types after severe epithelial injury. Life-long persistence of two stem cell populations brings about OE regeneration when damaged: the horizontal basal cells (HBCs), which are quiescent and held in reserve, and mitotically active globose basal cells (GBCs). Bot... read more
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