Low Oxygen Treatment for the Optimization of 3D Endothelial Cell Tissue Cultures.

Mijailovic, Aleksandar S.

2011

Description
  • Currently, the most salient challenge in tissue engineering is the inability to sufficiently vascularize engineered tissues. Without adequate vasculature, most tissues cannot survive due to lack of nutrient and oxygen diffusion. Thus, the therapeutic capability of tissue engineering remains limited. A number of studies have shown that mimicking in vivo oxygen tensions (4%-6%O2) promotes prolifera... read more
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