Differentially Modulating the VTA: A Role for Delta-mediated GABA(A) Tonic Inhibition and the Stress Neuropeptide CRF during Ethanol Intake

Darnieder, Laura.


  • Abstract: Binge drinking is a prevalent form of short-term alcohol consumption resulting in blood alcohol levels of 0.08 g/dl. Although more frequent in men, binge drinking has become increasingly common in women. To this end, sex-specific changes are evident in underlying mesocorticolimbic circuitry, including the modulation of GABAergic inhibitory neurotransmission. Broadly speaking, extrasynapt... read more
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