Stapled peptides: How to be quick on the uptake.

Kritzer, Joshua A.

2016.

Description
  • Stapled helices are promising compounds for inhibiting intracellular protein-protein interactions, but the discovery of peptides with the key property of cellular uptake has taken place largely through trial and error. A new study defines physicochemical parameters for designing hydrocarbon-stapled helices with a greater likelihood of cellular uptake.
This object is in collection Subject Permanent URL Citation
  • Kritzer, J.A. Stapled peptides: How to be quick on the uptake. Nat. Chem. Biol. 2016 12(10), 764-765. doi:10.1038/nchembio.2183.
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bn999k64f
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