Conformational Restriction of the NPF Motif to Target EHD1 and Endocytic Recycling

KAMENS, ALISSA.

2017

Description
  • Abstract: The development of specific inhibitors for the long-loop recycling pathway is critical for the study of vesicle trafficking and its involvement in the spread of metastasized cancer cells. Many of the proteins involved in this pathway are difficult to target due to the large and shallow protein-protein interactions they require to function. EHD1, a C-terminal EH domain-containing protein,... read more
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