Robust bioengineered 3D functional human intestinal epithelium.

Kaplan, David, 1953-

Chen, Ying.

Lin, Yinan.

Wang, Qianrui.

Rnjak-Kovacina, Jelena.

Li, Chunmei.

Isberg, Ralph R.

Kumamoto, Carol A.

Mecsas, Joan.

2015

Description
  • Intestinal functions are central to human physiology, health and disease. Options to study these functions with direct relevance to the human condition remain severely limited when using conventional cell cultures, microfluidic systems, organoids, animal surrogates or human studies. To replicate in vitro the tissue architecture and microenvironments of native intestine, we developed a 3D porous pr... read more
This object is in collection Subject Permanent URL Citation
  • Chen, Y. et al. Robust bioengineered 3D functional human intestinal epithelium. Sci. Rep. 5, 13708; doi: 10.1038/srep13708 (2015).
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