The role of the tissue microenvironment in resistance and susceptibility of the rat mammary gland to carcinogenesis

Sweeney, Michael.

2018

Description
  • Abstract: ABSTRACT N-nitrosomethylurea (NMU) administration to rats of several susceptible strains leads to rapid, reproducible, tumor production. The Copenhagen (COP) rat strain, however, is completely resistant to NMU carcinogenesis. The cause of this resistance is yet unknown. Using tissue recombination experiments, our lab has shown that the mammary gland stroma is the "gatekeeper" for tum... read more
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b27747077
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tufts:28636
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