Background: Adult mice have a remarkable capacity to regenerate
functional alveoli following either lung resection or injury that exceeds the
regenerative capacity observed in larger adult mammals. The molecular basis for this
unique capability in mice is largely unknown. We examined the transcriptomic
responses to single lung pneumonectomy ... read morein adult mice in order to elucidate
prospective molecular signaling mechanisms used in this species during lung
regeneration.
Paxson, Julia, Christopher D. Parkin, Lakshmanan K. Iyer,
Melissa R. Mazan, Edward P. Ingenito, and Andrew M. Hoffman. "Global gene expression
patterns in the post-pneumonectomy lung of adult mice." Respiratory Research 10, no.
1 (12, 2009): 1-15.