Background: In the knee, high-resolution magnetic resonance (MR) imaging
has demonstrated that increased apparent bone volume fraction (trabecular bone volume
per total volume; BV/TV) in the peri-articular proximal medial tibia is associated
with joint space narrowing and the presence of bone marrow lesions. However, despite
evidence of c... read moreonstruct validity, MR-based apparent BV/TV has not yet been
cross-validated in the proximal medial tibia by comparison with a gold standard
(e.g., micro-computed tomography [microCT]). In this cadaveric validation study we
explored the association between MR-based apparent BV/TV and microCT-based BV/TV in
the proximal peri-articular medial tibia.
Keywords: Micro-computed tomography, Validation, Magnetic resonance,
Driban, Jeffrey, Mary F. Barbe, Mamta Amin, Neil S. Kalariya,
Ming Zhang, Grace H. Lo, Anna M. Tassinari, Daniel Harper, Lori Lyn Price, Charles B.
Eaton, Erika Schneider, and Timothy E. McAlindon. "Validation of quantitative
magnetic resonance imaging-based apparent bone volume fraction in peri-articular
tibial bone of cadaveric knees." BMC Musculoskeletal Disorders 15, no. 1 (12, 2014):