The Roles Of The Origin Binding Domain in Polyoma Large T Function.

Banerjee, Pubali.


  • Abstract: Abstract Polyoma Large T (LT) is a multifunctional protein. It directly participates in the initiation of viral DNA replication and in integration, incision and excision of the viral genome in transformation. It regulates a variety of host cell processes including immortalization, differentiation and programmed cell death. LT can be separated into domains that retain independent function... read more
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