Construction of Hybrid Inhibitors for Metalloproteinase Targeting.

Quinto, Laura B.

2018

Description
  • Although cancer-promoting activities of extracellular proteases and peptidases in the tumor microenvironment are well known, the disruption of individual enzymes in this environment remains a fundamental challenge. To better understand the roles of these enzymes in cancer progression, and to potentially begin to target them in vivo, selective inhibitors of these enzymes are needed. Small molecules... read more
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9593v6201
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