GABAergic Control of the HPA axis as a Treatment Target for Epilepsy.

Wakefield, Seth.


  • Abstract: In response to stress, the hypothalamic pituitary adrenal (HPA) axis is activated and the stress hormone corticosterone is released from the adrenal gland in mice. Stress is a common trigger for seizures, and epileptic patients have increased levels of stress hormones. We hypothesize that HPA activation following a single seizure episode may result in future seizure susceptibility due to... read more
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