Relations between Vitamin B6, Tryptophan Metabolites, and Inflammation.

Reginaldo, Christina.


  • Abstract: Background: A variety of inflammatory conditions, including cardiovascular disease (CVD) and diabetes, and are associated with both increased kynurenine pathway (KP) activity and low plasma concentrations of pyridoxal 5'phosphate (PLP), the bioactive form of vitamin B6. Inflammatory cytokines induce the first enzyme in the KP; downstream enzymes require PLP as a cofactor to produce immun... read more
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