Epigenetic Regulation of Mammary Epithelial Differentiation and Lineage Plasticity.

Skibinski, Adam.


  • Abstract: Lineage-committed cells of many tissues exhibit substantial plasticity in contexts such as wound healing and tumorigenesis, but the regulation of this process is not well understood. Here, I studied the molecular mechanisms that either allow mammary epithelial cells (MECs) to transdifferentiate or dedifferentiate in specific contexts. I identified the Hippo transducer WWTR1/TAZ in a screen ... read more
This object is in collection Creator department Thesis Type Genre Permanent URL
To Cite:
DCA Citation Guide    EndNote