Background: Signaling via B cell receptor (BCR) and Toll-like receptors
(TLRs) results in activation of B cells with distinct physiological outcomes, but
transcriptional regulatory mechanisms that drive activation and distinguish these
pathways remain unknown.
Fowler, Trent, Alexander S. Garruss, Amalendu Ghosh, Supriyo
De, Kevin G. Becker, William H. Wood, Matthew T. Weirauch, Stephen T. Smale, Bruce
Aronow, Ranjan Sen, and Ananda L. Roy. "Divergence of transcriptional landscape
occurs early in B cell activation." Epigenetics & Chromatin 8, no. 1 (12, 2015):