PDF | Non-stem cancer cell kinetics modulate solid tumor progression. | ID: 8910k5858

Non-stem cancer cell kinetics modulate solid tumor progression.

Morton, Charles I.

Hlatky, Lynn.

Hahnfeldt, Philip.

Enderling, Heiko.

2011

Description

Background: Solid tumors are heterogeneous in composition. Cancer stem cells (CSCs) are believed to drive tumor progression, but the relative frequencies of CSCs versus non-stem cancer cells span wide ranges even within tumors arising from the same tissue type. Tumor growth kinetics and composition can be studied through an agent-based ... read more

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Morton, Charles, Lynn Hlatky, Philip Hahnfeldt, and Heiko Enderling. "Non-stem cancer cell kinetics modulate solid tumor progression." Theoretical Biology and Medical Modelling 8, no. 1 (12, 2011): 1-13.