Uncovering features that control selective protein glycation.

Sjoblom, Nicole.


  • Posttranslational modifications (PTMs) are covalent alterations of proteins following host cell synthesis and they have key functional roles implicated in several diseases. In this work, we examine two unique and understudied PTMs: glycation and bacterial effector-mediated phosphoribosylation. Glycation, the spontaneous addition of reducing sugars or sugar metabolites onto proteins, has been ... read more
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