Curcumin and piperine supplementation of obese mice under caloric restriction modulates body fat and interleukin-1β.

Miyazawa, Taiki.

Nakagawa, Kiyotaka.

Kim, Sharon H.

Thomas, Michael J.

Paul, Ligi.

Zingg, Jean-Marc.

Dolnikowski, Gregory G.

Roberts, Susan B.

Kimura, Fumiko.

Miyazawa, Teruo.

Azzi, Angelo.

Meydani, Mohsen.


  • Background: Dietary bioactive compounds capable of improving metabolic profiles would be of great value, especially for overweight individuals undergoing a caloric restriction (CR) regimen. Curcumin (Cur), a possible anti-obesity compound, and piperine (Pip), a plausible enhancer of Cur's bioavailability and efficacy, may be candidate agents for controlling body fat, metabolism and low grade ... read more
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