Multi-scale engineering and modeling of heterologous natural product biosynthesis in Escherichia coli.

Boghigian, Brett.


  • Abstract: The engineering of biological systems for industrial applications is a complex process. Optimization of a cellular phenotype is complicated by the sheer number of genetic and environmental variables. With regards to heterologous natural product biosynthesis, this is further complicated by the foreign nature of the metabolic pathways and structurally complex products involved. To address ... read more
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