Determining Cellular and Molecular Targets of the Yersinia Tyrosine Phosphatase YopH During Animal Infection.

Durand, Enrique.


  • Abstract: The gram-negative enteric pathogen Yersinia pseudotuberculosis employs a type III secretion system that is required to translocate proteins essential for virulence, called Yops (Yersinia outer proteins), into host cells. Yops are efficiently translocated to a wide variety of cells grown in culture and most interact with many different mammalian proteins in different cell types; however t... read more
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